Skip to main content

Table 2 Longitudinal lung function assessment of cohort

From: MMP-2 and TIMP-1 predict healing of WTC-lung injury in New York City firefighters

Time

Variable

Controls

Resistant

p

Pre-9/11

FEV1%

98 (90–108)

117(108–124)

<0.0001

 

FEV1/FVC

84 (81–87)

87 (84–89)

<0.0001

MME

FEV1%

91 (81–96)

105(97–113)

<0.0001

 

FEV1/FVC

84 (79–87)

85 (83–89)

<0.0001

SPE

FEV1%

93 (83–98)

113 (109–119)

<0.0001

 

FEV1/FVC

77 (73–79)

81 (79–84)

<0.0001

 

BD response

5 (2–10)

5(2–9)

0.776

 

BD response > 12%, N (%)

13/46 (28)

5/23 (22)

0.772

 

MCT slope

0.64 (0.31-0.15)

0.04(0.02-0.07)

0.010

 

PC20 < 10 mg/mL MCT, N (%)

17/86 (20)

6/66 (9)

0.108

 

TLC

103 (95–109)

106 (103–116)

0.016

 

RV,% Pred

125 (113–141)

111 (103–123)

0.015

 

DLCO

106 (99–114)

116 (108–131)

0.001

 

VA

93 (85–98)

100 (95–105)

<0.0001

 

DLCO/VA

120 (107–130)

110 (107–126)

0.358

  1. FEV1 Forced expiratory volume in one second, FVC Forced vital capacity, MCT Methacholine, BD Bronchodilator, PC20 concentration of methacholine causing a 20% fall in FEV1, DLCO Diffusion capacity of the lung for carbon monoxide, VA Alveolar volume.