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Table 3 Overview of the hitstological and Immunohistochemical score

From: Bifidobacterium breve and Lactobacillus rhamnosus treatment is as effective as budesonide at reducing inflammation in a murine model for chronic asthma

Group Inflammation (HE) Goblet cells (PAS) Connective tissue (Masson) α-smooth muscle cells (anti-α-smooth muscle actin) Proliferating cells (anti-Ki67)
OVA/Sal-PBS - - - + -
OVA/OVA-PBS ++ + ++ ++ ++
OVA/Sal-B. breve - - + + +/-
OVA/OVA-B. breve + + + ++ +
OVA/Sal-L. rhamnosus - - + + +/-
OVA/OVA-L. rhamnosus + + + ++ +/-
OVA/Sal-budesonide - - + + +/-
OVA/OVA-budesonide + - + ++ +
  1. Slides were reviewed in blinded fashion by two observers independently and slides were scored on the basis of the percentage of positive stained cells in the following way: -,no positive staining; +/-, less than 25% of cells stained positive; +,25 to 50% cells stained positive; ++, 50 to 75% cells stained positive. Results are presented as average score of 5 animals/group.