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Table 6 Serum markers of inflammation and myokines

From: A randomized clinical trial to assess the influence of a three months training program (Gym-based individualized vs. Calisthenics-based non-invidualized) in COPD-patients

  IT p-value NT p-value p-value
M1 M2 M1 M2
CRP [mg/l] 5.6 + 2.1 6.2 + 2.4 1.000 5 + 0 5.2 + 0.6 0.180 0.419
WBC [G/l] 7.5 + 2.1 7.4 + 2.3 0.619 7.2 + 2.1 6.9 + 2.1 0.198 0.666
IL-6 [ng/l] 4.9 + 7.9 3.6 + 2.1 0.324 3.8 + 3.1 5.8 + 6.4 0.170 0.653
IL-8 [ng/l] 8.4 + 3.0 8.8 + 2.9 0.569 8.8 + 2.8 9.4 + 3.6 0.362 0.691
TNF-α [ng/l] 9.9 + 3.5 9.1 + 2.9 0.528 10.7 + 2.9 10.7 + 3.1 0.889 0.587
PGC1- α [relative copies] 0.77 ± 0.77 1.2 ± 1.15 0.017 1.03 ± 0.77 1.16 ± 0.81 0.388 0.832
Irisin [ng/μl] 128.65 ± 14.87 131.5 ± 33.26 0.528 123.67 ± 17.85 128.86 ± 16.68 0.136 0.138
  1. Wilcoxon rank-sum test for paired samples was used to test for significant differences between measurement 1 (M1: before the program) and measurement 2 (M2: after the program). To compare the deltas (M2-M2) between both groups, the Mann–Whitney-U-Test for unpaired samples was performed. Abbreviations are explained in the text.