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Table 2 Subjects characteristics used for primary culture

From: Regenerative defect in vastus lateralis muscle of patients with chronic obstructive pulmonary disease

Characteristics

Control (n = 7)

COPD (n = 8)

Age

63 ± 2.3

66 ± 2.3

BMI (kg/m 2 )

29.1 ± 2.4

28.8 ± 2.0

FEV 1 , L

3.3 ± 0.2

1.0 ± 0.1a

FEV 1, % predicted

106.3 ± 4.1

37.0 ± 4.0a

FEV 1 /FVC, %

76 ± 1.6

36.5 ± 1.1a

TLC, % predicted

98.6 ± 6.5

118.0 ± 5.5

RV, % predicted

90.1 ± 15.3

163.5 ± 15.9a

DL CO , % predicted

96.9 ± 3.2

53.3 ± 5.8a

MTCSA (cm 2 )

120.3 ± 3.4

82.3 ± 6.5a

Satellite cells (Pax7+/100 fibers)

2.6 ± 0.4

1.7 ± 0.3a

Central nuclei (count/100 fibers)

4.0 ± 0.8

6.5 ± 1.0a

  1. Values are means ± SEM.
  2. astatistically significant difference from control (p < 0.05).
  3. Definition of abbreviations: BMI Body mass index, FEV 1 Forced expiratory volume in 1 second, TLC total lung capacity, RV Residual volume, DLCO Diffusing capacity of carbon monoxide, MTCSA Mid-thigh cross-sectional area.
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Respiratory Research

ISSN: 1465-993X

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