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Figure 2 | Respiratory Research

Figure 2

From: Regulation of transplanted mesenchymal stem cells by the lung progenitor niche in rats with chronic obstructive pulmonary disease

Figure 2

Morphometric analysis of HE-stained lung tissue. (I, ×100; II, ×200). A) normal control group; B) COPD group; C) COPD + 60CO γ irradiation + MSCs transplantation group; D) COPD + rAAV-SPA-TK injection + 60CO γ irradiation + MSC transplantation group; E) COPD + AAV injection + 60CO γ irradiation + MSC transplantation group. In group B, there was a decreased alveolar number (MAN), enlarged mean linear intercept (MLI), and increased pulmonary alveolar area (PAA). There were no statistical differences among groups B, C, D and E for MAN, MLI, and PAA. However, in group D, there was high cell infiltration. Scale bars = 100 μm. The results are expressed as the mean ± SD, n = 10 in each group. *P < 0.01, **P < 0.05.

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