Skip to main content

Table 3 The association of α-tocopherol (α-T) and γ-tocopherol (γ-T) with lung spirometry (year 0 of the CARDIA study)

From: The vitamin E isoforms α-tocopherol and γ-tocopherol have opposite associations with spirometric parameters: the CARDIA study

  Lung spirometry BLACKSa WHITESa ALL PARTICIPANTSb
N βc SE 95% confidence interval P value N β SE 95% confidence interval P value N β SE 95% confidence interval P value
α-T   2289      2237      4526     
  FEV1   27.6 17.3 -6.3 to 61.6 0.11 #   5.5 13.7 -21.4 to 32.4 0.69   11.1 10.8 -10.1 to 32.3 0.30
  FVC   40.4 19.7 1.9 to 78.9 0.04*   33.4 16.0 2.1 to 64.7 0.04*   31.3 12.5 6.8 to 55.8 0.01*
  FEV1/FVC   -0.1 0.3 -0.6 to 0.4 0.78   -0.4 0.2 -0.8 to -0.0 0.03*   -0.3 0.2 -0.6 to 0.0 0.07 #
γ-T   2289      2237      4526     
  FEV1   -80.0 37.7 -154.0 to -6.0 0.03*   -78.0 47.1 -170.3 to 14.3 0.10 #   -73.7 29.5 -131.6 to -15.8 0.01*
  FVC   -106.7 42.8 -190.7 to -22.7 0.01*   -107.8 54.8 -215.3 to -0.4 0.05*   -97.0 34.1 -163.9 to -30.0 0.005*
  FEV1/FVC   0.3 0.5 -0.8 to 1.4 0.59   0.2 0.7 -1.1 to 1.5 0.74   0.2 0.4 -0.6 to 1.1 0.58
  1. (Linear regression analysis at year 0 of the CARDIA study).
  2. aAdjustments: center, age, age2, height, height2, sex, BMI, smoking status and ever asthma.
  3. bAdjustments: center, age, age2, height, height2, sex, BMI, smoking status and ever asthma, race.
  4. cβ is the difference in mL of FEV1, mL of FVC or % FEV1/FVC per 10 μM tocopherol.
  5. *and boldface, significant; #and boldface, trend.