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Figure 6 | Respiratory Research

Figure 6

From: Rosiglitazone is a superior bronchodilator compared to chloroquine and β-adrenoceptor agonists in mouse lung slices

Figure 6

Rosiglitazone and chloroquine maintain efficacy following overnight incubation with CQ or RGZ. Slices were incubated overnight with vehicle (0.1% water for chloroquine (CQ), 0.1% DMSO for rosiglitazone (RGZ)) or CQ (100 μM) or RGZ (100 μM). Airways were pre-contracted with 100 nM methacholine (MCh) prior to addition of albuterol (ALB, 10 μM) or CQ (100 μM) or RGZ (100 μM). A) Relaxation response to ALB and RGZ following overnight incubation with RGZ (n = 3/group). B) Relaxation response to ALB and CQ following CQ incubation overnight (n = 3/group).

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