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Figure 1 | Respiratory Research

Figure 1

From: Rosiglitazone is a superior bronchodilator compared to chloroquine and β-adrenoceptor agonists in mouse lung slices

Figure 1

Rosiglitazone and chloroquine elicit concentration-dependent relaxation in mouse small airways in lung slices. Airways in lung slices were pre-contracted with 100 nM methacholine (MCh), prior to perfusion with chloroquine (CQ) or rosiglitazone (RGZ). Representative traces showing changes in airway lumen area during A) cumulative perfusion and B) sequential additions of CQ. C) D) Grouped data for CQ (n = 4/group) and RGZ (n = 4/group) added cumulatively or sequentially. Responses (mean ± S.E.M) represent the% relaxation of the pre-contraction to MCh, averaged over the last minute of perfusion at each dilator concentration.

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Respiratory Research

ISSN: 1465-993X

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