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Figure 5 | Respiratory Research

Figure 5

From: Inhibition of mTORC1 induces loss of E-cadherin through AKT/GSK-3β signaling-mediated upregulation of E-cadherin repressor complexes in non-small cell lung cancer cells

Figure 5

EMT in Raptor-silenced cells. (A) Phase contrast and immunocytochemical image of scrambled and Raptor shRNA-transduced A5549 and H2009 cells (X1,000). E-cadherin: Red, Vimentin: Green. (B) Expression of EMT markers α-smooth muscle actin (SMA), Vimentin, and N-cadherin were evaluated in scrambled and Raptor shRNA-transduced A549 and H2009 cells by Western blotting. β-actin was used as a loading control. (C) Illustration of the role of mTORC1 in the regulation of mTORC2-mediated EMT.

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Respiratory Research

ISSN: 1465-993X

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