Table 4 Linear regression analysis of COPD patients with plasma sRAGE as dependent variable
From: Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD
Univariate analysis | B | 95% CI for B | p value |
Age | 0.010 | -0.005 to 0.025 | 0.190 |
Sex | -0.076 | -0.325 to 0.173 | 0.547 |
Pack years | 0.002 | -0.006 to 0.010 | 0.630 |
BMI | -0.008 | -0.032 to 0.015 | 0.480 |
FEV1 | 0.010 | 0.003 to 0.017 | 0.007 |
FEV1/VC | 0.012 | 0.004 to 0.019 | 0.004 |
LTOT | -0.329 | -0.640 to -0.017 | 0.039 |
GFR | -0.006 | -0.011 to 0.000 | 0.069 |
CRP | -0.004 | -0.019 to 0.011 | 0.584 |
DLCO | 0.014 | 0.006 to 0.023 | 0.002 |
Multivariate analysis | B | 95% CI for B | p value |
Model 1: Age + sex | -0.096 | -0.345 to 0.153 | 0.444 |
Model 2: model 1 + FEV1 | 0.010 | 0.003 to 0.017 | 0.006 |
Model 3: model 2 + DLCO | 0.012 | 0.002 to 0.022 | 0.017 |
Model 4: model 3 + LTOT | -0.414 | -0.781 to -0.047 | 0.028 |
Multivariate analysis | B | 95% CI for B | p value |
Model 1: Age + sex | -0.96 | -0.346 to 0.153 | 0.444 |
Model 2: model 1 + FEV1/VC | 0.012 | 0.004 to 0.019 | 0.004 |
Model 3: model 2 + DLCO | 0.011 | 0.001 to 0.021 | 0.026 |
Model 4: model 3 + LTOT | -0.427 | -0.787 to -0.066 | 0.021 |