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Table 1 The effect of DEP 50 on median EGFR ligand gene expression

From: Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles

 

AR median (IQR)

HB-EGF median (IQR)

TGFα median (IQR)

SFM

2.8 (1.5-3.2)

2.0 (1.8-2.4)

2.2 (1.8–3.1)

DEP 6 h

4.1 (1.1-9.2)

4.1 (2.6-5.2)

1.5 (1.3–7.1)

DEP 18 h

2.2 (1.2-3.2)

2.0 (1.8-5.8)

4.0 (1.8–5.9)*

  1. PBECs were exposed to DEP 50 μg/ml for 6 or 18 h and mRNA levels of the EGFR ligands determined by RT-qPCR. *p < 0.05, n = 10.
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Respiratory Research

ISSN: 1465-993X

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