Table 4 Odds ratios for CMH in sex stratified adjusted* analyses

Total methylation

1.23

(1.07, 1.41)

0.004**

1.28

(1.07, 1.54)

0.008

1.23

(1.11, 1.37)

<.0001**

SULF2

2.72

(1.51, 4.91)

0.001**

2.97

(1.48, 5.95)

0.002**

2.73

(1.75, 4.25)

<.0001**

p16

2.08

(1.01, 4.28)

0.048

1.66

(0.71, 3.89)

0.246

1.88

(1.09, 3.23)

0.023

JPH3

2.64

(1.43, 4.87)

0.002**

2.70

(0.96, 7.59)

0.059

2.66

(1.58, 4.48)

<.0001**

PCDH20

1.68

(0.94, 2.98)

0.079

2.29

(1.15, 4.53)

0.018

1.89

(1.22, 2.93)

0.004**

Females

LSC n =  673

PLuSS n =  307

Combined n =  980

Exposure variable

OR

(95 % CL)

p value

OR

(95 % CL)

p value

OR

(95 % CL)

p value

Total methylation

1.04

(0.96, 1.14)

0.324

1.08

(0.93, 1.25)

0.322

1.05

(0.98, 1.13)

0.188

SULF2

1.41

(0.97, 2.05)

0.074

1.72

(0.96, 3.07)

0.066

1.47

(1.07, 2.01)

0.016

p16

1.25

(0.79, 1.99)

0.342

1.76

(0.91, 3.40)

0.091

1.41

(0.97, 2.05)

0.073

JPH3

1.07

(0.71, 1.62)

0.748

1.20

(0.42, 3.39)

0.736

1.10

(0.75, 1.62)

0.634

PCDH20

1.33

(0.92, 1.93)

0.126

1.35

(0.72, 2.52)

0.346

1.34

(0.97, 1.83)

0.073