Skip to main content

Table 1 Select variables by CMH status in the LSC

From: Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion

LSC

Total

CMH

No CMH

 
 

n = 900

(100.0)

n = 311

(100.0)

n = 589

(100.0)

 

Characteristic

n or mean

(%) or (SD)

n or mean

(%) or (SD)

n or mean

(%) or (SD)

p value

Female

673

(74.8)

222

(71.3)

451

(76.6)

0.088

Baseline age

55.9

(9.6)

55.1

(9.8)

56.3

(9.4)

0.067

Education > = HS*

663

(73.7)

207

(66.6)

456

(77.4)

<0.001

Obese

278

(30.9)

93

(29.9)

185

(31.4)

0.642

Pack years

41.1

(20.9)

44.2

(21.8)

39.5

(20.2)

0.001

Baseline smoker

494

(55.6)

236

(76.4)

258

(44.6)

<.0001

Baseline COPD

281

(31.2)

123

(39.6)

158

(26.8)

<.0001

Total methylation

2.47

(2.12)

2.66

(2.22)

2.37

(2.06)

0.057

PCDH20

333

(37.0)

125

(40.2)

208

(35.3)

0.149

SULF2

299

(33.2)

122

(39.2)

177

(30.1)

0.005

GATA4

348

(38.7)

125

(40.2)

223

(37.9)

0.495

PAX5A

138

(15.3)

46

(14.8)

92

(15.6)

0.743

p16

154

(17.1)

61

(19.6)

93

(15.8)

0.147

MGMT

249

(27.7)

87

(28.0)

162

(27.5)

0.881

DAPK

153

(17.0)

54

(17.4)

99

(16.8)

0.833

GATA5

152

(16.9)

55

(17.7)

97

(16.5)

0.643

PAX5B

90

(10.0)

30

(9.7)

60

(10.2)

0.797

DAL1

71

(7.9)

27

(8.7)

44

(7.4)

0.521

JPH3

229

(25.4)

91

(29.3)

138

(23.4)

0.056

  1. *High school.