Importance of Aspergillus spp. isolation in Acute exacerbations of severe COPD: prevalence, factors and follow-up: the FUNGI-COPD study

Table 4 Significant univariate and multivariate logistic regression analysis for the prediction of Aspergillus spp. risk factors

	Univariate analysis			Multivariate analysis
	OR	95%CI	p-value	OR	95%CI	p-value
Arterial hypertension	6.48	1.17-35.84	0.032	4.72	1.56-14.39	0.001
Cardio vascular disease	9.97	1.30-76.47	0.027	-	-	-
Diabetes mellitus	3.52	1.77-15.94	0.041	-	-	-
Chronic renal disease	2.92	2.23-15.35	0.070	-	-	-
COPD exacerbation in the previous year ^§	2.60	1.16-6.11	0.050	12.35	1.87-29.14	<0.001
Previous bacterial colonization	3.50	1.47-8.37	0.002	-	-	-
Concurrent PPM isolation ^£	2.92	1.42-6.84	0.024	3.64	1.65-9.45	0.001
Concurrent P. aeruginosa isolation	2.10	1.21-5.68	0.042	2.80	1.81-11.42	0.001

^§COPD exacerbation that required hospital management (emergency room visit or admission).
^£PPM, Pathogenic microorganisms.

ISSN: 1465-993X