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Table 3 Effects of drugs on cytokine secretion by BE cells from all subjects (mean , 95% CI, n = 17)

From: Budesonide and formoterol effects on rhinovirus replication and epithelial cell cytokine responses

Mock-infected Drugs
None Budesonide Formoterol Both
CXCL8 3940 (3454, 4426) 3546 (2935, 4157) 4279 (3901, 4657) 3780 (3292, 4268)
CXCL10 7.2 (5.3, 9.8) 2.7 (1.6, 4.6)** 3.8 (2.4, 6.1)** 3.3 (1.8, 5.8)**
TNFα 6.7 (3.9, 11) 0.5 (0.2, 1.4)** 2.4 (0.7, 7.8)* 0.8 (0.2, 2.6)**
RV-infected     
CXCL8 4163 (3540, 4786) 3504 (2993, 4015)** 4116 (3675, 4557) 3634 (3164, 4104)*
CXCL10 44 (7.0, 249) 29 (9.8, 84) 34 (11, 112) 34 (12, 99)
TNFα 8.1 (4.7, 14) 1.5 (0.5, 4.6)** 2.7 (0.8, 9.2)** 1.3 (0.4, 4.4)**
IFNBI mRNA 2.2 (1.4, 3.2) 2.0 (1.2, 3.8) 2.8 (1.8, 4.3) 2.6 (1.7, 4.0)
IL28 mRNA 32 (14, 74) 19 (8.9, 42) 24 (9.4, 61) 17 (6.7, 42)
  1. CXCL8 arithmetic mean, others represent geometric means; cytokine protein values represent pg/mL, and mRNA are presented as fold increase after RV infection.
  2. * P ≤ 0.05 drug vs. no drug.
  3. ** P ≤ 0.005 drug vs. no drug.