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Table 3 Frequencies and percentages of number of cristae and number of cristae divided by length

From: Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

  Number of cristae per mitochondrion per section FRQ/L**
  0 < 3 3-6 >6 Mean ± SD Mean ± SD
Control 0 (0.0%) 0 (0.0%) 2 (6.7%) 28 (93.3%) 2.9 ± 0.3 2.2 ± 0.8
1% CSE 0 (0.0%) 2 (6.5%) 9 (29.0%) 20 (64.5%) 2.6 ± 0.6 1.9 ± 0.6
2.5% CSE 4 (12.5%) 4 (12.5%) 8 (25%) 16 (50%) 2.1 ± 1.1* 1.7 ± 1.0*
10% CSE 4 (11.8%) 5 (14.7%) 19 (55.9%) 6 (17.6%) 1.8 ± 0.9* 1.3 ± 0.8*
12.5% CSE 0 (0.0%) 5 (14.3%) 18 (51.4%) 12 (34.3%) 2.2 ± 0.7* 1.6 ± 0.6*
-10% CSE 1 (3.3%) 4 (13.3%) 12 (40%) 13 (43.3%) 2.2 ± 0.8* 1.6 ± 0.7*
  *** **** ****
  1. *p < 0.05 pairwise comparison to 0% CSE (Control).
  2. **Frequency divided by length.
  3. ***Estimated by chi-square test (p < 0.001).
  4. ****Estimated by One-Way ANOVA test (p < 0.001).
  5. BEAS-2B cells were exposed to various concentrations of cigarette smoke extract (CSE) for 6 months and subjected to EM analysis. Representative images of BEAS-2B cells exposed to: 0% CSE (control), 1% CSE, 2.5% CSE, 10% CSE, 12.5% CSE and -10% CSE are shown in Figure 1. In total of 30–35 mitochondria were analyzed per experimental condition. Significance was determined by chi-square test and One-Way ANOVA.