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Table 1 Characteristics of the subjects: primary bronchial epithelial cells (PBECs)

From: Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

Subject Control non-smoker Control smoker GOLD stage IV
n 15 15 24
Age 55,5 (43–76) 51.6 (40–70) 59,7 (48–71)
Gender M (%) 7 (46.7%) 12 (80%) 10 (41.7%)
Pack-years 0 (0–0) 31.3 (11–60) 39.3 (11–80)
  1. All PBECs included in the study were provided by Lonza or the NORM and TIP study within the University Medical Center Groningen. COPD patients were included on a basis of FEV1 < 50% of predicted, FEV1/FVC < 70% and ≥20 pack-years for GOLD stage IV. All control subjects had FEV/FVC > 70% and FEV1 > 90% of predicted. FEV/FVC, FEV1 predicted and pack-years from Lonza cells are unknown.