Subject | Control non-smoker | Control smoker | GOLD stage IV |
---|
n
| 15 | 15 | 24 |
Age
| 55,5 (43–76) | 51.6 (40–70) | 59,7 (48–71) |
Gender M (%)
| 7 (46.7%) | 12 (80%) | 10 (41.7%) |
Pack-years
| 0 (0–0) | 31.3 (11–60) | 39.3 (11–80) |
- All PBECs included in the study were provided by Lonza or the NORM and TIP study within the University Medical Center Groningen. COPD patients were included on a basis of FEV1 < 50% of predicted, FEV1/FVC < 70% and ≥20 pack-years for GOLD stage IV. All control subjects had FEV/FVC > 70% and FEV1 > 90% of predicted. FEV/FVC, FEV1 predicted and pack-years from Lonza cells are unknown.