|
Subject
|
Control non-smoker
|
Control smoker
|
GOLD stage IV
|
|---|
|
n
|
15
|
15
|
24
|
|
Age
|
55,5 (43–76)
|
51.6 (40–70)
|
59,7 (48–71)
|
|
Gender M (%)
|
7 (46.7%)
|
12 (80%)
|
10 (41.7%)
|
|
Pack-years
|
0 (0–0)
|
31.3 (11–60)
|
39.3 (11–80)
|
- All PBECs included in the study were provided by Lonza or the NORM and TIP study within the University Medical Center Groningen. COPD patients were included on a basis of FEV1 < 50% of predicted, FEV1/FVC < 70% and ≥20 pack-years for GOLD stage IV. All control subjects had FEV/FVC > 70% and FEV1 > 90% of predicted. FEV/FVC, FEV1 predicted and pack-years from Lonza cells are unknown.
