Figure 4

miR-21 is increased in lung alveolar type II cells from idiopathic pulmonary fibrosis (IPF) patients. (A) Representative flow cytometric analyses of CD45^- VE-cadherin^- lung cells for the isolation of human alveolar type II cells (CD45^- VE-cadherin^- EpCAM⁺ T1-α^- cells) from the non-fibrotic lungs of patients without fibrotic lung diseases and the fibrotic lungs of patients with IPF. (B) The relative expression of microRNAs is shown. The values represent the mean ± SEM (n = 3). The values relative to those of the human alveolar type II cells from non-fibrotic lungs are presented. The data were analyzed with Student’s t-test. * p < 0.05 versus the non-fibrotic lung group.