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Table 3 Quantification and statistical significance of monocyte migration and pSmad 2/3 staining data

From: Differential regulation of cell functions by CSD peptide subdomains

Monocytes Peptide Migration Statistical significance pSmad 2/3 Statistical significance
Normal Control 20.1 ± 2.5   26.3 ± 1.1  
Normal CSD 12.6 ± 2.1 p < 0.05 vs Normal/Control 16.4 ± 0.5 p < 0.01 vs Normal/Control
Normal Cav-A 48.4 ± 7.8 p < 0.01 vs Normal/Control 31.0 ± 1.1 p < 0.05 vs Normal/Control
Normal Cav-B 35.4 ± 4.5 p < 0.01 vs Normal/Control 16.6 ± 1.6 p < 0.01 vs Normal/Control
Normal Cav-C 27.1 ± 2.1   19.1 ± 1.5 p < 0.01 vs Normal/Control
Normal Cav-AB 37.8 ± 8.7 p < 0.05 vs Normal/Control 26.8 ± 1.4  
Normal Cav-BC 32.6 ± 5.1 p < 0.05 vs Normal/Control 18.4 ± 1.2 p < 0.01 vs Normal/Control
Normal + TGFβ Control 99.9 ± 11.7 p < 0.001 vs Normal/Control 43.1 ± 0.9 p < 0.01 vs Normal/Control
Normal + TGFβ CSD 18.7 ± 4.5 p < 0.01 vs Normal + TGFβ/Control 21.2 ± 1.2 p < 0.01 vs Normal + TGFβ/Control
Normal + TGFβ Cav-A 47.4 ± 5.5 p < 0.01 vs Normal + TGFβ/Control 37.7 ± 1.2  
Normal + TGFβ Cav-B 47.6 ± 4.4 p < 0.01 vs Normal + TGFβ/Control 40.7 ± 1.2  
Normal + TGFβ Cav-C 36.2 ± 3.0 p < 0.01 vs Normal + TGFβ/Control 43.0 ± 1.1  
Normal + TGFβ Cav-AB 37.7 ± 3.5 p < 0.01 vs Normal + TGFβ/Control 39.0 ± 1.5  
Normal + TGFβ Cav-BC 25.9 ± 5.7 p < 0.01 vs Normal + TGFβ/Control 18.7 ± 1.4 p < 0.01 vs Normal + TGFβ/Control
SSc Control 303 ± 32 p < 0.001 vs Normal/Control 54.1 ± 1.0 p < 0.01 vs Normal/Control
SSc CSD 77 ± 10 p < 0.01 vs SSc/Control 37.6 ± 0.7 p < 0.01 vs SSc/Control
SSc Cav-A 334 ± 44   49.1 ± 3.1  
SSc Cav-B Not Done   48.4 ± 1.5  
SSc Cav-C Not Done   49.3 ± 1.2  
SSc Cav-AB Not Done   46.1 ± 3.0  
SSc Cav-BC 138 ± 24 p < 0.02 vs SSc/Control 36.6 ± 1.4 p < 0.01 vs SSc/Control
  1. Data from Figure 2 (migration) and Figure 3 (image analyses of pSmad 2/3 staining) are presented in terms of average value ± s.e.m. The statistical significance of the indicated comparisons were determined using Students’ t test.