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Table 1 Characteristics participants included in sample 1 and sample 2

From: GST-omega genes interact with environmental tobacco smoke on adult level of lung function

 

Sample 1

Sample 2 (verification)

n

8128

5308

Males, n (%)

3483 (43)

2133 (40)

Age, median (min-max)

47 (18–89)

48 (21–90)

Smoking status, n (%)

  

  Never, n (%)

3277 (40)

2154 (41)

  Ex, n (%) [median (min-max)]

2882 (36) [8 (0–86)]

2014 (39) [7 (0–100)]

  Current, n (%) [median (min-max)]

1936 (24) [15 (0–100)]

1065 (20) [16 (0–81)]

ETS exposure, n (%)

  

  In utero

867 (13)

559 (13)

  ≥ 1 hour/day

1788 (24)

1029 (21)

  At the workplace

565 (7)

303 (6)

Lung function, mean (sd)

  

  FEV1 (ml)

3412 (831)

3331 (840)

  FEV1pp (%)1

102 (14)

102 (14)

  FEV1/FVC (%)

77 (7)

76 (7)

Spirometry available, n

7635

5070

  1. The second sample (sample 2) was used to verify the initial findings from sample 1, both samples are part of the LifeLines population-based cohort study.
  2. 1 FEV1pp = FEV1 as percentage predicted based on reference equations constructed by Quanjer et al. [28].