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Figure 5 | Respiratory Research

Figure 5

From: Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses

Figure 5

Treatment with sivelestat alters cytokine and growth factor levels in BAL fluid 48 hr after secondary challenge. The levels of (A) IL-4, (B) IL-5, (C) IL-13, (D) TGF-β1, (E) Eotaxin, (F) KC, and (G) MIP-2 in BAL fluid were measured. The results for each group are expressed as the mean ± SD. (n = 16 in each group). *Significant differences (P<0.05) between PBS/OVA/vehicle/OVA and OVA/OVA/vehicle/OVA. #Significant differences (P < 0.05) between OVA/OVA/vehicle/OVA and OVA/OVA/Sivelestat/OVA.

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Respiratory Research

ISSN: 1465-993X

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