Figure 1From: HTR4 gene structure and altered expression in the developing lungImmunohistochemistry of 5-HT 4 R in normal adult human lung tissue. Low cytoplasmic and membranous expression of 5-HT4R was found in the pneumocytes of the alveoli in all three normal lung samples (a-c). The epithelium showed variable staining; donor 1 had very weak cytoplasmic staining (g), donor 2 had strong cytoplasmic and nuclear staining of >50% of nuclei (h), whilst donor 3 had weak staining in <20% of epithelial cells (i). All isotype controls were negative (d-f and j-l). X40 magnification.Back to article page