Table 2 The inhibitory effect of 10-6 M methylprednisolone (MP) alone and in combination with 2.5 ng/mL Cyclosporin A (CsA) on IFNγ and TNFα expression by T, NKT-like and NK cells are shown (mean ± SEM)
IFNγ | TNFα | ||||||
|---|---|---|---|---|---|---|---|
Drug | Dose of drug | T | NKT | NK | T | NKT | NK |
MP | 10-6 M | 2 ± 2* | 5 ± 3 | 44 ± 8 | 2 ± 2 | 3 ± 2 | 47 ± 9 |
CsA | 2.5 ng/ml | 47 ± 9 | 44 ± 7 | 91 ± 5 | 51 ± 6 | 31 ± 9 | 92 ± 8 |
MP + CsA | 10-6 M + 2.5 ng/ml | 88 ± 7 | 83 ± 7 | 96 ± 6 | 81 ± 7 | 76 ± 7 | 96 ± 8 |