Skip to main content

Table 3 Comparison of LABA (+) and LABA (−) patients in the propensity-matched cohort

From: Long-acting beta-agonists reduce mortality of patients with severe and very severe chronic obstructive pulmonary disease: a propensity score matching study

  LABA (−) LABA (+)  
N 246 246 P
Age (year) 66.7 ± 5.0 66.8 ± 5.3 0.732
Sex (female) 86 (35.0%) 85 (34.6%) 0.925
Race (not white) 10 (4.1%) 12 (4.9%) 0.663
Annual income < 30000 $ 125 (50.8%) 123 (50.0%) 0.857
FEV1 (%predicted) 26.5 ± 6.8 26.6 ± 6.8 0.991
[FEV1 (mL)] 766 ± 222 777 ± 242 0.866
[FEV1/FVC (%)] 31.0 ± 6.0 31.2 ± 6.3 0.926
FVC (%predicted) 67.1 ± 15.4 67.0 ± 15.0 0.849
[FVC (mL)] 2527 ± 757 2556 ± 802 0.772
Forced residual capacity (mL) 6072 ± 1330 6040 ± 1306 0.842
Hb adjusted DLCO 7.9 ± 2.9 8.1 ± 3.2 0.632
[Peak pulmonary arterial pressure(mmHg)] 34.0 ± 6.0 33.3 ± 6.2 0.202
Hemoglobin (g/dL) 14.4 ± 1.2 14.4 ± 1.3 0.626
PaO2 (mmHg) 64.2 ± 10.0 64.2 ± 10.2 0.829
PaCO2 (mmHg) 43.1 ± 5.8 43.0 ± 5.4 0.972
[Area of emphysema (%)] 16.3 ± 11.1 16.0 ± 9.5 0.759
Body mass index (kg/m^2) 24.7 ± 3.5 24.7 ± 3.6 0.860
Six-minute walk distance (m) 366 ± 93 371 ± 98 0.577
St. George respiratory questionnaire 53.4 ± 12.5 53.3 ± 12.6 0.974
Shortness of breath questionnaire 63.0 ± 17.9 63.0 ± 19.0 0.961
Beck depression inventory 9.1 ± 5.8 9.0 ± 5.8 0.988
Recent emergency visit 33 (13.4%) 30 (12.2%) 0.686
Recent hospital stay 19 (7.7%) 17 (6.9%) 0.729
LTOT during sleep 173 (70.3%) 170 (69.1%) 0.769
LTOT on exertion 191 (77.6%) 191 (77.6%) 1.000
Oral corticoid 70 (28.5%) 62 (25.2%) 0.416
Inhaled corticosteroid 186 (75.6%) 186 (75.6%) 1.000
Short-acting beta-agonist 219 (89.0%) 217 (88.2%) 0.777
Anticholinergic agent 205 (83.3%) 203 (82.5%) 0.811
Theophylline 103 (41.9%) 94 (38.2%) 0.408
Diuretics 34 (13.8%) 38 (15.4%) 0.610
  1. [parameters]: parameters not used in logistic regression analysis for propensity score matching were shown in brackets.
  2. Parameters were compared with Wilcoxon rank sum test or Chi-square test.
  3. FEV1: forced expiratory volume in one second.
  4. FVC: forced vital capacity.
  5. Hb adjusted DLCO: hemoglobin adjusted diffusing capacity of the lung for carbon monoxide.
  6. PaO2: pressure of oxygen in artery.
  7. PaCO2: pressure of carbon dioxide in artery.
  8. LTOT: long-term oxygen therapy.