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Table 3 Comparison of LABA (+) and LABA (−) patients in the propensity-matched cohort

From: Long-acting beta-agonists reduce mortality of patients with severe and very severe chronic obstructive pulmonary disease: a propensity score matching study

 

LABA (−)

LABA (+)

 

N

246

246

P

Age (year)

66.7 ± 5.0

66.8 ± 5.3

0.732

Sex (female)

86 (35.0%)

85 (34.6%)

0.925

Race (not white)

10 (4.1%)

12 (4.9%)

0.663

Annual income < 30000 $

125 (50.8%)

123 (50.0%)

0.857

FEV1 (%predicted)

26.5 ± 6.8

26.6 ± 6.8

0.991

[FEV1 (mL)]

766 ± 222

777 ± 242

0.866

[FEV1/FVC (%)]

31.0 ± 6.0

31.2 ± 6.3

0.926

FVC (%predicted)

67.1 ± 15.4

67.0 ± 15.0

0.849

[FVC (mL)]

2527 ± 757

2556 ± 802

0.772

Forced residual capacity (mL)

6072 ± 1330

6040 ± 1306

0.842

Hb adjusted DLCO

7.9 ± 2.9

8.1 ± 3.2

0.632

[Peak pulmonary arterial pressure(mmHg)]

34.0 ± 6.0

33.3 ± 6.2

0.202

Hemoglobin (g/dL)

14.4 ± 1.2

14.4 ± 1.3

0.626

PaO2 (mmHg)

64.2 ± 10.0

64.2 ± 10.2

0.829

PaCO2 (mmHg)

43.1 ± 5.8

43.0 ± 5.4

0.972

[Area of emphysema (%)]

16.3 ± 11.1

16.0 ± 9.5

0.759

Body mass index (kg/m^2)

24.7 ± 3.5

24.7 ± 3.6

0.860

Six-minute walk distance (m)

366 ± 93

371 ± 98

0.577

St. George respiratory questionnaire

53.4 ± 12.5

53.3 ± 12.6

0.974

Shortness of breath questionnaire

63.0 ± 17.9

63.0 ± 19.0

0.961

Beck depression inventory

9.1 ± 5.8

9.0 ± 5.8

0.988

Recent emergency visit

33 (13.4%)

30 (12.2%)

0.686

Recent hospital stay

19 (7.7%)

17 (6.9%)

0.729

LTOT during sleep

173 (70.3%)

170 (69.1%)

0.769

LTOT on exertion

191 (77.6%)

191 (77.6%)

1.000

Oral corticoid

70 (28.5%)

62 (25.2%)

0.416

Inhaled corticosteroid

186 (75.6%)

186 (75.6%)

1.000

Short-acting beta-agonist

219 (89.0%)

217 (88.2%)

0.777

Anticholinergic agent

205 (83.3%)

203 (82.5%)

0.811

Theophylline

103 (41.9%)

94 (38.2%)

0.408

Diuretics

34 (13.8%)

38 (15.4%)

0.610

  1. [parameters]: parameters not used in logistic regression analysis for propensity score matching were shown in brackets.
  2. Parameters were compared with Wilcoxon rank sum test or Chi-square test.
  3. FEV1: forced expiratory volume in one second.
  4. FVC: forced vital capacity.
  5. Hb adjusted DLCO: hemoglobin adjusted diffusing capacity of the lung for carbon monoxide.
  6. PaO2: pressure of oxygen in artery.
  7. PaCO2: pressure of carbon dioxide in artery.
  8. LTOT: long-term oxygen therapy.