Loss of alveolar membrane diffusing capacity and pulmonary capillary blood volume in pulmonary arterial hypertension

Table 4 Correlations among clinical markers and lung diffusion capacity and its components at baseline

Variables	DL_CO(ml/min/mmHg)	DL_NO(ml/min/mmHg)	D_m(ml/min/mmHg)	V_c(ml)
BNP (pg/ml)	R = 0.3	R = −0.01	R = −0.01	R = 0.5
	P = 0.2	P = 0.9	P = 0.9	p = 0.02
6-MWD (m)	R = 0.5	R = 0.4	R = 0.4	R = 0.3
	p = 0.05	p = 0.1	p = 0.1	P = 0.2
Left ventricular fractional shortening (%)	R = −0.3	R = −0.3	R = −0.3	R = −0.3
	p = 0.1	p = 0.2	p = 0.2	p = 0.3
Left ventricular ejection fraction (%)	R = −0.1	R = −0.1	R = −0.1	R = −0.2
	p = 0.6	p = 0.6	p = 0.6	p = 0.4
Right ventricular systolic pressure (mmHg)	R = 0.09	R = −0.1	R = −0.1	R = 0.3
	p = 0.7	p = 0.6	p = 0.6	p =0.2
Right ventricular end diastolic area (cm²)	R = 0.2	R = 0.07	R = 0.07	R = 0.4
	p = 0.3	p = 0.7	p = 0.7	p = 0.04
Right ventricular end systolic area (cm²)	R = 0.2	R = 0.07	R = 0.07	R = 0.4
	p = 0.4	p = 0.8	p = 0.8	p = 0.04
Right ventricular fractional area change (%)	R = −0.2	R = −0.2	R = −0.2	R = −0.3
	p = 0.3	p = 0.4	p = 0.4	p = 0.09
RV fractional shortening (%)	R = −0.2	R = −0.2	R = −0.2	R = −0.3
	p = 0.4	p = 0.4	p = 0.4	p = 0.1
Right ventricular outflow tract velocity time interval (cm)	R = −0.3	R = −0.2	R = −0.2	R = −0.1
	p = 0.2	p = 0.4	p = 0.4	p = 0.6
Mean pulmonary arterial pressure (mmHg)	R = 0.2	R = 0.06	R = 0.06	R = 0.4
	p = 0.3	p = 0.8	p = 0.8	p = 0.05
Mean pulmonary capillary wedge pressure (mmHg)	R = 0.2	R = −0.05	R = −0.05	R = 0.2
	p = 0.5	p = 0.8	p = 0.8	p = 0.4
Cardiac output (L/min)	R = −0.3	R = −0.4	R = −0.4	R = −0.2
	p = 0.3	p = 0.1	p = 0.1	p = 0.5
Pulmonary vascular resistance (wood units)	R = 0.2	R = 0.2	R = 0.2	R = 0.3
	p = 0.4	p = 0.4	p = 0.4	p = 0.1

ISSN: 1465-993X