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Table 4 Correlations among clinical markers and lung diffusion capacity and its components at baseline

From: Loss of alveolar membrane diffusing capacity and pulmonary capillary blood volume in pulmonary arterial hypertension

Variables DLCO(ml/min/mmHg) DLNO(ml/min/mmHg) Dm(ml/min/mmHg) Vc(ml)
BNP (pg/ml) R = 0.3 R = −0.01 R = −0.01 R = 0.5
  P = 0.2 P = 0.9 P = 0.9 p = 0.02
6-MWD (m) R = 0.5 R = 0.4 R = 0.4 R = 0.3
  p = 0.05 p = 0.1 p = 0.1 P = 0.2
Left ventricular fractional shortening (%) R = −0.3 R = −0.3 R = −0.3 R = −0.3
  p = 0.1 p = 0.2 p = 0.2 p = 0.3
Left ventricular ejection fraction (%) R = −0.1 R = −0.1 R = −0.1 R = −0.2
  p = 0.6 p = 0.6 p = 0.6 p = 0.4
Right ventricular systolic pressure (mmHg) R = 0.09 R = −0.1 R = −0.1 R = 0.3
  p = 0.7 p = 0.6 p = 0.6 p =0.2
Right ventricular end diastolic area (cm2) R = 0.2 R = 0.07 R = 0.07 R = 0.4
  p = 0.3 p = 0.7 p = 0.7 p = 0.04
Right ventricular end systolic area (cm2) R = 0.2 R = 0.07 R = 0.07 R = 0.4
  p = 0.4 p = 0.8 p = 0.8 p = 0.04
Right ventricular fractional area change (%) R = −0.2 R = −0.2 R = −0.2 R = −0.3
  p = 0.3 p = 0.4 p = 0.4 p = 0.09
RV fractional shortening (%) R = −0.2 R = −0.2 R = −0.2 R = −0.3
  p = 0.4 p = 0.4 p = 0.4 p = 0.1
Right ventricular outflow tract velocity time interval (cm) R = −0.3 R = −0.2 R = −0.2 R = −0.1
  p = 0.2 p = 0.4 p = 0.4 p = 0.6
Mean pulmonary arterial pressure (mmHg) R = 0.2 R = 0.06 R = 0.06 R = 0.4
  p = 0.3 p = 0.8 p = 0.8 p = 0.05
Mean pulmonary capillary wedge pressure (mmHg) R = 0.2 R = −0.05 R = −0.05 R = 0.2
  p = 0.5 p = 0.8 p = 0.8 p = 0.4
Cardiac output (L/min) R = −0.3 R = −0.4 R = −0.4 R = −0.2
  p = 0.3 p = 0.1 p = 0.1 p = 0.5
Pulmonary vascular resistance (wood units) R = 0.2 R = 0.2 R = 0.2 R = 0.3
  p = 0.4 p = 0.4 p = 0.4 p = 0.1
  1. 6-MWD: 6 minute walk distance.
  2. BNP: brain natriuretic peptide.
  3. DL: lung diffusion for carbon monoxide (DLCO) and for nitric oxide (DLNO).
  4. Dm: alveolar-capillary membrane diffusing capacity.
  5. Vc: lung capillary blood volume.