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Table 1 Baseline characteristics of the two study groups

From: Loss of alveolar membrane diffusing capacity and pulmonary capillary blood volume in pulmonary arterial hypertension

Variable Healthy PAH p-value
  N = 41 N = 28  
Age (years) 34 ±2 45 ±2 <0.01
Gender (M/F) 17/24 6/22 0.09
Smoking history (never/current/ex smoker) 40/0/1 24/1/3 0.1
Height (cm) 169 ±1 167 ±3 0.3
Weight (kg) 79 ±3 89 ±7 0.2
O2 Saturation (% of Hgb) 98 ±0.2 96 ±0.4 <0.01
FENO (ppb) 19 ±2 18 ±2 0.7
FVC (%) 98 ±2 91 ±3 0.2
FEV1 (%) 93 ±2 80 ±4 <0.01
FEV1/FVC 81 ±1 75 ±1 <0.01
TLC (%) 85 ±2 82 ±2 0.4
VA (L) 4.9 ±0.2 4.3 ±0.2 0.1
DLCO (ml/min/mmHg) 24 ±1 17 ±1 <0.01
DLNO (ml/min/mmHg) 94 ±4 66 ±5 <0.01
Dm (ml/min/mmHg) 48 ±2 33 ±2 <0.01
Vc (ml) 78 ±4 63 ±5 <0.01
Dm/Vc (1/min/mmHg) 0.6 ±0.02 0.6 ±0.04 0.8
Hgb (g/dl) 13.3 ±0.3 13.5 ±0.4 0.9
  1. F/M: female/male.
  2. FENO: fractional exhaled nitric oxide.
  3. FVC: forced vital capacity.
  4. FEV1: forced expiratory volume in one second.
  5. TLC: total lung capacity.
  6. VA: alveolar volume.
  7. DL: lung diffusion for carbon monoxide (DLCO) and for nitric oxide (DLNO).
  8. Dm: alveolar-capillary membrane diffusing capacity.
  9. Vc: lung capillary blood volume.
  10. Hgb: hemoglobin.
  11. PAH: pulmonary arterial hypertension.