The minimal important difference of the pulmonary functional status and dyspnea questionnaire in patients with severe chronic obstructive pulmonary disease

Table 2 Baseline values, changes and correlations of changes in PFSDQ-M and CRDQ scores and 6MWD from baseline to 3-months rehabilitation program

	N = 301		PFSDQ-M activity component	PFSDQ-M dyspnea component	PFSDQ-M fatigue component
	Baseline values	ΔChanges from baseline to 3-month PR	- 6 ± 7	- 5 ± 7	- 5 ± 7
CRDQ dyspnea	15 ± 4	6 ± 5	- 0.32*‡	- 0.30*‡	- 0.34*‡
CRDQ fatigue	15 ± 4	3 ± 3	- 0.27‡	- 0.23 ‡	- 0.21‡
CRDQ total	78 ± 16	16 ± 12	- 0.42*‡	- 0.41*‡	- 0.41*‡
6MWD (m)	396 ± 124	47 ± 89	- 0.30*‡	- 0.26‡	- 0.27‡

Data for changes are expressed in mean ± SD. SD standard deviation, PR pulmonary rehabilitation, PFSDQ-M pulmonary functional status and dyspnea questionnaire modified version, CRDQ chronic respiratory disease questionnaire, 6MWD six minute walking distance.
Pearson correlation coefficient, ‡p < 0.0001. *Values indicate sufficient correlation for using the anchor based method (linear regression analyses).

ISSN: 1465-993X