Figure 8
From: Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats
Effect of endostatin on alveolar epithelial cell apoptosis. (A-D) Representative co-immunofluorescence for TUNEL (A), SP-C (B) and DAPI (C) identifies apoptotic alveolar type II cells (D, merge) from a lung section. (E-G) Representative fluorescent micrographs for in SA (E), BLM (F) and E-ES (G) groups on day 7 (×400) are shown. (F) Quantitative assessment of alveolar type II cell apoptosis among different experimental groups on days 7 and 28 were presented. Bar = 100μm. Results are expressed as mean ± SD, n = 5 in each group, *P < 0.001 vs SA group; #P < 0.05 vs BLM group; +P < 0.001 vs BLM group.