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Table 3 Soluble adhesion molecules in BAL fluid and sputum

From: Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study

 

Controls

Smokers without COPD

Smokers with COPD

BAL fluid

ICAM-1

94.8

94.3

47.6*, §

(ng/mL)

84.3-122.7

78.0-149.9

29.1-86.1

ICAM-3

15.1

16.1

12.4

(pg/mL)

9.6-26.2

8.7-26.1

10.6-18.8

PECAM-1

285.5

758.6§,

351.4*

(pg/mL)

194.2-684.1

525.7-1037.1

217.1-512.9

VCAM-1

281.5

122.4

114.4

(pg/mL)

118.5-484.9

103.9-204.7

75.2-293.9

Sputum supernatant (ng/mL)

ICAM-1

16.6

16.6

33.6

<5.0-42.7

<5.0-34.4

<5.0-51.9

ICAM-3

17.1

20.3

28.7

14.1-60.5

<11.0-43.2

10.3-49.3

E-selectin

< 4.0

< 4.0

12.5

<4.0-17.7

<4.0-13.0

<4.0-23.1

P-selectin

< 19.0

< 19.0

< 19.0

<19.0 - 40.9

< 19.0 -25.5

PECAM-1

12.2

9.0

13.4

6.6-23.8

< 4.0-13.8

< 4.0-18.0

VCAM-1

7.1

< 5.0

8.5

5.1-7.8

<5.0-8.7

<5.0-12.0

  1. Results are expressed as ng/mL; median and 25th- 75th percentiles.
  2. § p< 0.05 compared to non-smoking controls.
  3. * p< 0.05 compared to smokers without COPD.