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Table 2 Cell distribution in blood, bronchoalveolar lavage and induced sputum

From: Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study

 

Controls

Smokers without COPD

Controls vs Smokers without COPD p-value

Smokers with COPD

Controls vs Smokers with COPD p-value

Blood (cells x10 3 /mL)

Monocytes

512

597

ns

616

ns

363-741

482-674

516-790

Neutrophils

2914

3633

0.2

4072

0.01

2121-4188

2942-3889

3456-5392

*0.04

Lymphocytes

1828

2442

ns

2189

ns

1675-2752

1857-3148

 

1942-2624

Eosinophils

184

255

ns

269

ns

117-249

135-318

236-334

BAL (cells x10 6 /L)

Cells x10 6 /L

114

290

0.0001

281

0.002

83.2-129

259-523

156-351

 

Macrophages

91.3

264

0.0001

242

0.001

79.1-115.7

225-498

143-305

Neutrophils

3.8

12.4

0.03

8.4

0.04

0.4-5.1

3.5-21.5

3.6-21.7

Lymphocytes

4.7

13.3

0.003

10.2

0.2

3.6-8.9

11.2-23.5

3.3-19.8

Eosinophils

0

0

0.2

2.4

0.01

0-0.2

0-1.1

0.3-4.5

Sputum (cells/mg)

Cells/mg

715

603

ns

652

ns

514-908

284-866

409-1370

Macrophages

250

218

ns

234

ns

155-603

53.5-444

136-424

Neutrophils

396

415

ns

501

ns

157-490

132-591

343-786

Lymphocytes

23.2

9.3

ns

14.9

ns

18.2-31.8

7.2-11.3

4.5-55.6

Eosinophils

0

1.3

ns

8.2

ns

0-5.0

0-2.6

0.6-16.8

  1. Data are presented as median and 25th – 75th percentile. Comparisons between groups were made using Kruskal-Wallis test followed by Mann–Whitney test when appropriate. * indicate p-value for comparison between smokers with and without COPD.