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Table 3 Studies of mortality within 30 days after the surgical lung biopsy procedure

From: The current position of surgical lung biopsy in the diagnosis of idiopathic pulmonary fibrosis

Study

Patients

Type of biopsy

Number of biopsies/Period

Mortality 30 days (90 days)

Risk factors

Utz et al., Eur Respir J 2001

IPF = 46

OLB 73%

No of biopsies not described

- 16.7% in total population

- 4/10 had AE-IPF before SLB

CTD-UIP = 14

VATS 27%

1986-1995

- All IPF

- Lower DLCO

- 21.7% in IPF

Lettieri et al., Chest 2005

IPF = 42

OLB (no?)

No of biopsies not described

- 4.8%

- Mechanical ventilation

Non-IPF = 41

VATS (no?)

1996-2002

(5/6%)

- Immunologic treatment

- No difference IPF vs non-IPF, VATS vs OLB

Tiitto et al., Chest 2005

IPF = 64

OLB n = 42

1

- OLB 5.3%

- OLB

CTD-UIP = 12

VATS n = 34

1973-2002

- VATS 0%

Park et al., Eur J Cardio-Thorac Surg 2007

IPF = 140

OLB n = 50

2-3

- 4%

- AE-IPF

NSIP = 46

VATS n = 150

1990-2003

(8%)

- DLCO < 50%

COP = 14

No ICU patients

Sigurdsson et al., Ann Thorac Surg 2009

UIP = 23

OLB n = 45

1: 70%

- 3%

- No data of different ILDs

OP = 17

VATS n = 28

2: 20%

(4%)

NSIP = 6

1986-2007

- No difference OLB vs VATS

Others = 27

Fibla et al., Int J Cardiovasc Thorac Surg 2012

IPF = 122

OLB 10%

1: 16%

VATS 9%

- Age > 67

 

COP = 31

VATS 90%

2: 64%

OLB 10.6%

- OLB

 

RBILD = 16

 

3: 59%

 

- Immunologic treatment

 

NSIP = 13

 

4: 1%

 

- No data of different ILDs

 

Others = 114

 

2002-2009

  
 

6% in ICU

    
  1. Abbreviations:
  2. AE-IPF acute exacerbation of idiopathic pulmonary fibrosis.
  3. COP cryptogenic organizing pneumonia.
  4. CTD-ILD connective tissue associated interstitial lung disease.
  5. DLCO diffusion capacity.
  6. ILD interstitial lung disease.
  7. ICU intensive care unit.
  8. IPF idiopathic pulmonary fibrosis.
  9. NSIP nonspecific interstitial pneumonia.
  10. OLB open lung thoracotomy.
  11. RBILD respiratory bronchiolitis and interstitial lung disease.
  12. SLB surgical lung biopsy.
  13. VATS video-assisted thoracoscopic operation.