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Table 4 Correlations between gas trapping measures and quantitative outcomes in subjects with severe emphysema (Insp -950HU > 15% ex-smokers, Insp -950HU > 14% current smokers)

From: Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD

  Correlations
  N Mean (SD) Exp−856 E/I MLA RVC856-950 Residual
FEV1 % predicted 1185 41.2 (19.9) −0.69‡ −0.73‡ −0.73‡ −0.16‡
FVC % predicted 1185 75.7 (21.1) −0.49‡ −0.56‡ −0.57‡ −0.17‡
FEV1/FVC 1185 0.40 (0.12) −0.66‡ −0.62‡ −0.62‡ −0.08*
FEF25-75 1185 0.42 (0.38) −0.56‡ −0.61‡ −0.61‡ −0.18‡
FRC/TLC ratio 1188 0.69 (0.12) 0.80* 0.93* 0.87* 0.44*
6MWD 1135 1116 (404) −0.31‡ −0.40‡ −0.43‡ −0.01NS
Exacerbation frequency 1188 0.8 (1.2) 0.10† 0.12‡ 0.13‡ −0.02NS
SGRQ total 1188 44.9 (19.9) 0.32‡ 0.41‡ 0.43‡ 0.09*
MMRC dyspnea 1183 2.5 (1.3) 0.34‡ 0.38‡ 0.42‡ 0.01NS
  1. Pearson correlation coefficients are shown.
  2. *p < 0.01.
  3. †p < 0.001.
  4. ‡p < 0.0001.
  5. NS = not significant (p > 0.05).