Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression

Respiratory Research

Table 4 Characteristics of BAL subjects used for in vitro stimulation studies

Group	Smokers	Never-smokers	pvalue
Subjects, n	5	4
Sex ratio, M/F	5/0	2/2	0.13
Age, years (SD)	60 (11)	39.5 (12.1)	0.06
Smoking, pack-years (SD)	47.4 (35.2)	0 (0)	0.02
Smoking status (Former/Current)	0/5	0/0	0.007
FEV₁, % pred. (SD)	66.6 (30.6)	106.5 (12)	0.06
FEV1/FVC% (SD)	61.8 (19)	81.0 (7.5)	0.10
ICS use (yes/no)	3/2	0/4	0.10

ICS Inhaled Corticosteroid Use, M Male, F Female. Data are represented as mean (SD), ratio of current smokers to former smokers, or fraction of ICS users (yes/no). All FEV1 values are pre-bronchodilator. p values calculated using Mann Whitney test.

ISSN: 1465-993X