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Table 4 Characteristics of BAL subjects used for in vitro stimulation studies

From: Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression

Group Smokers Never-smokers pvalue
Subjects, n 5 4  
Sex ratio, M/F 5/0 2/2 0.13
Age, years (SD) 60 (11) 39.5 (12.1) 0.06
Smoking, pack-years (SD) 47.4 (35.2) 0 (0) 0.02
Smoking status (Former/Current) 0/5 0/0 0.007
FEV1, % pred. (SD) 66.6 (30.6) 106.5 (12) 0.06
FEV1/FVC% (SD) 61.8 (19) 81.0 (7.5) 0.10
ICS use (yes/no) 3/2 0/4 0.10
  1. ICS Inhaled Corticosteroid Use, M Male, F Female. Data are represented as mean (SD), ratio of current smokers to former smokers, or fraction of ICS users (yes/no). All FEV1 values are pre-bronchodilator. p values calculated using Mann Whitney test.