Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression

Respiratory Research

Table 2 Characteristics of BAL subjects used for flow cytometry studies

Group	Smokers	Never-smokers	pvalue
Subjects, n	13	10
Sex ratio, M/F	11/2	1/9	0.0006
Age, years (SD)	60.3 (8.9)	42.2 (13.7)	0.002
Smoking, pack-years (SD)	47.4 (33.7)	0 (0)	0.0001
Smoking status (Former/Current)	3/10	0/0	0.0001
FEV₁, % pred. (SD)	83.5 (23.6)	100.7 (10.5)	0.077
FEV1/FVC% (SD)	72.5 (14.3)	84.2 (5.7)	0.0249
ICS use (yes/no)	4/9	0/10	N.S.

ICS Inhaled Corticosteroid Use; M Male, F Female. Data are represented as mean (SD), ratio of current smokers to former smokers, or fraction of ICS users (yes/no). All FEV1 values are pre-bronchodilator. p values calculated using Mann Whitney test.

ISSN: 1465-993X