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Table 1 Characteristics of BAL subjects used for RNA studies

From: Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression

Group Smokers Never-smokers pvalue
Subjects, n 11 6  
Sex ratio, M/F 11/0 2/4 0.003
Age, years (SD) 65.5 (7.2) 37.7 (12) 0.002
Smoking, pack-years (SD) 65.5 (23.1) 0 (0) 0.0008
Smoking status (Former/Current) 2/9 0/0 0.003
FEV1, % pred. (SD) 57 (22.1) 101 (8.7) 0.002
FEV1/FVC% (SD) 58.5 (15.6) 86.8 (4.9) 0.0007
ICS use (yes/no) 7/4 0/6 0.02
  1. ICS Inhaled Corticosteroid Use, M Male, F Female. Data are represented as mean (SD), ratio of current smokers to former smokers, or fraction of ICS users (yes/no). All FEV1 values are pre-bronchodilator. p values calculated using Mann Whitney test.