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Figure 2 | Respiratory Research

Figure 2

From: Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression

Figure 2

AMø TLR3 expression does not correlate with lung function or total duration of smoking exposure. AMø were harvested, processed and analyzed as described in the legend to Figure 1. A-C. TLR3 mRNA transcripts by quantitative real-time PCR (smokers, n = 11; never-smokers, n = 6, except in panel C, which includes only current or former smokers). D-F. Flow cytometric analysis of TLR3 protein expression (smokers, n = 13; never-smokers, n = 10, except in panel F which includes only current or former smokers). A, D: FEV1 % predicted; B, E: participant age (years); C, F: smoking history (pack-years); note the difference in the vertical scale of panel F. Blue circles, smokers; red crosses, never-smokers. p values by Spearman correlation.

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Respiratory Research

ISSN: 1465-993X

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