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Table 2 Vitamin D insufficiency and clinical characteristics of asthma

From: Severe and uncontrolled adult asthma is associated with vitamin D insufficiency and deficiency

 

25(OH)D < 30 ng/ml

25(OH)D ≥ 30 ng/ml

p-value

Allergy

   

Yes

159 (67.4%)

77 (32.6%)

 

No

28 (66.7%)

14 (33.3%)

0.359

OCS use

   

Yes

58 (77.3%)

17 (22.7%)

 

No

130 (63.4%)

75 (36.6%)

0.031

OCS dose (mg/d)

24 ± 29

16 ± 12

0.274

ICS use

   

Yes

150 (68.2%)

70 (31.8%)

 

No

38 (63.3%)

22 (36.7%)

0.536

ICS dose (μg/d)

1310 ± 815

1232 ± 916

0.547

Age (years)

44.5 ± 13.0

46.0 ± 15.4

0.400

FEV1 (L)

2.3 ± 0.9

2.7 ± 1.0

0.003

FEV1 (%)

71.7 ± 23.4

81.4 ± 22.3

0.001

Reversibility (%)

13.1 ± 22.7

12.2 ± 23.3

0.838

Exhaled NO (ppb)

45 ± 46

31 ± 27

0.022

Total IgE (IU/ml)

544 ± 1292

365 ± 689

0.230

Duration of disease (years)

18.6 ± 13.5

17.5 ± 15.5

0.539

Sputum eosinophilia

   

Yes

21 (95.5%)

1 (4.5%)

 

No

36 (66.7%)

18 (33.3%)

0.008

Sputum eosinophils (%)

5.1 ± 11.9

0.5 ± 1.0

0.005

BMI (kg/m 2 )

28.3 ± 6.3

25.1 ± 3.9

<0.001

IL-10 (ng/ml)

118.6 ± 122.6

114.2 ± 137.1

0.788

  1. Displayed are means ± SD for continuous endpoints and frequencies for categorical endpoints.