Skip to main content

Table 3 Multiple linear regression models to evaluate the factors associated with baseline and final values of 6MWD

From: Three-year follow-up of Interleukin 6 and C-reactive protein in chronic obstructive pulmonary disease

Variables Baseline 6MWD p-value Final 6MWD p-value
Coefficient (95% CI) Coefficient (95% CI)
Gender (Male) 48.36 (8.61, 88.10) 0.02 22.64 (−26.55, 71.84) 0.35
Age (years) −1.40 (−4.77, 1.96) 0.40 −0.60 (−4.88, 3.66) 0.77
FEV1 (%) 1.57 (0.74, 2.40) <0.001 1.88 (0.82, 2.95) <0.001
IL-6 (pg/ml) −42.02 (−65.49, -22.56) <0.001 −54.86 (−82.40, -27.32) <0.001
Charlson index −8.81 (−33.77, 16.18) 0.48 −11.52 (−43.31, 20.25) 0.46
  1. Baseline (R2 = 0.52; p ≤ 0.05) and after three years (R2 = 0.44; p ≤ 0.05). Definition of abbreviations: 6MWD = six-minute walking distance; FEV1 = forced expiratory volume in the first second (% of predicted); IL-6 = Interleukin 6. For both regression analysis the variables values were those obtained at baseline.