Three-year follow-up of Interleukin 6 and C-reactive protein in chronic obstructive pulmonary disease

Respiratory Research

Table 1 Characteristics of COPD patients followed for a three-year period

Variables	Initial assessment (n = 53)	Final assessment (n = 53)	p-value
FEV₁ (%)	56.0 ± 21.1	56.0 ± 22.6	0,48
FEV₁ (l)	1.4 ± 0.7	1.3 ± 0.6	0.03
FVC (%)	88.9 ± 20.9	86.3 ± 24.3	0.20
FVC (l)	2.6 ± 0.9	2.5 ± 0.9	0.01
FEV₁/FVC	50.5 ± 12.1	50.2 ± 10.6	0.49
SpO₂ (%)	93.0 ± 3.1	91.6 ± 4.9	0.02
MMRC (score)	1.6 ± 1.0	2.0 ± 1.2	0.01
6MWD (m)	444.0 ± 82.8	406.3 ± 102.9	<0.001
BMI (kg/m²)	25.6 ± 5.5	25.5 ± 5.4	0.38
BODE index	2.4 ± 1.9	2.9 ± 2.5	0.01

Comparisons of patient characteristics at baseline and after three years were performed by Paired t-test or Wilcoxon; p ≤ 0.05. Values are presented as mean ± SD. Definition of abbreviations: FEV₁ = forced expiratory volume in the first second (% of predicted); FVC = forced vital capacity (% of predicted); SpO₂ = pulse oximeter oxygen saturation; MMRC = Modified Medical Research Council; 6MWD = six-minute walking distance; BMI = body mass index.

ISSN: 1465-993X