Skip to main content

Advertisement

Table 3 Changes in pulmonary function, 6-minute walk test, and health-related quality of life before and after 12 weeks of pulmonary rehabilitation in patients with interstitial lung disease vs. chest Wall disease

From: Exercise training with negative pressure ventilation improves exercise capacity in patients with severe restrictive lung disease: a prospective controlled study

  Non-NPV-exercise group NPV-exercise group
Baseline 12 weeks Baseline 12 weeks
FVC, % predicted     
 ILD 40.3 ± 10.3 38.4 ± 13.5 36.3 ± 13.0 40.5 ± 11.6b, c
 Chest wall 32.7 ± 8.6 37.0 ± 14.5 28.0 ± 8.5 28.3 ± 7.4
FEV1, % predicted     
 ILD 45.6 ± 11.8 43.8 ± 18.2 40.9 ± 15.8 45.9 ± 15.2a
 Chest wall 35.3 ±11.3 44.2 ± 20.2 31.9 ± 8.6 33.3 ± 8.0
FEV1/FVC, %     
 ILD 81.8 ± 6.8 84.4 ±7.9 82.3 ± 9.7 81.0 ±11.8
 Chest wall 88.8 ± 10.6 82.2 ± 8.1 83.8 ± 9.7 86.6 ± 9.1
6MWD, m     
 ILD 385.2 ± 82.6 355.3 ± 85.0 352.3 ± 52.8 399.5 ± 45.1a
 Chest wall 318.2 ± 122.4 288.0 ± 99.3 395.0 ± 99.9 412.8 ± 109.8
SaO2, % pre/post 6MWT     
 ILD 94.3/ 78.7 93.1/ 78.6 96.0/80.5 96.3/83.1
 Chest wall 94.8/ 77.3 93.3/ 73.3 91.3/72.6 92.4/74.1
Borg, pre/ post 6MWT     
 ILD 0.9/ 5.1 1.5/5.8 1.7/ 5.5 0.8/4.8
 Chest wall 2.0/ 5.8 1.7/5.8 1.1/ 5.3 0.8/5.0
SGRQ     
 Symptom score     
  ILD 47.6 ± 21.5c 42.1 ± 19.3c 61.7 ± 16.6e 29.5 ± 19b,e
  Chest wall 50.3 ± 5.8d 64.1 ± 0.2d 53.7 ± 5.8f 45.9 ± 5.6a,f
 Active score     
  ILD 62.2 ± 21.5 73.7 ± 12.8 61.4 ± 27.4 53.5 ± 23.2
  Chest wall 59.5 ± 0.0 66.4 ± 18.8 43.9 ± 17.6 36.5 ± 22.0
 Impacts score     
  ILD 29.3 ± 13.6 43.9 ± 19.2 48.3 ± 25.3 30.0 ± 25.3a
  Chest wall 32.9 ± 16.7 58.0 ± 38.9 21.2 ± 11.7 13.5 ± 12.2
 Total score     
  ILD 42.3 ± 16.0 52.6 ± 14.0 54.5 ± 21.3 37.0 ± 21.1a
  Chest wall 43.8 ± 9.8 61.6 ± 26.4 32.2 ± 10.0 21.3 ± 11.5a
  1. Values are mean ± SD.
  2. a p < 0.05, baseline vs. 12 weeks; b p < 0.01, baseline vs. 12 weeks; cn = 8; dn = 2; en = 10; fn = 8.