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Figure 3 | Respiratory Research

Figure 3

From: Epigenetics of hypoxic pulmonary arterial hypertension following intrauterine growth retardation rat: epigenetics in PAH following IUGR

Figure 3

Immunohistochemical staining for a-SMA in lung tissue sections. Representative lung histological sections of Control d1 (A), IUGR d1 (B), Control 6wks (C), IUGR 6wks (D), Control hypoxia (E), and IUGR hypoxia (F) are shown demonstrating hypertrophy of the arterial medial wall induced by hypoxia. Note significant medial thickness (E and F), especially in IUGR hypoxia group (x 200). The bar graph represents the medial/(medial + lumen) thickness ratios of the small pulmonary arteries in various group rats, *P < 0.05 as compared with control d1, and IUGR d1, respectively; **P < 0.05 as compared with control d1, IUGR d1, Control 6wks, IUGR 6wks, and Control hypoxia, respectively. PA = pulmonary artery. (n = 10).

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