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Table 1 Mediators measured in sputum samples

From: Sputum mediator profiling and relationship to airway wall geometry imaging in severe asthma

Mediators included in analysis

Not measurable in >50 % of samples, excluded

Factor VII

Brain-Derived Neurotrophic Factor (BDNF)

Fibrinogen

C-Reactive Protein (CRP)

Ferritin (FRTN)

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)

Intercellular Adhesion Molecule 1 (ICAM-1)

Interferon gamma (IFN-gamma)

Interleukin-1 alpha (IL-1 alpha)

Interleukin-17 (IL-17)

Interleukin-1 beta (IL-1 beta)

Interleukin-2 (IL-2)

Interleukin-1 receptor antagonist (IL-1ra)

Interleukin-3 (IL-3)

Interleukin-6 (IL-6)

Interleukin-4 (IL-4)

Interleukin-8 (IL-8)

Interleukin-5 (IL-5)

Interleukin-15 (IL-15)

Interleukin-7 (IL-7)

Interleukin-18 (IL-18)

Interleukin-10 (IL-10)

Monocyte Chemotactic Protein 1 (CCL2)

Interleukin-12 Subunit p70 (IL-12p70)

Macrophage Inflammatory Protein-1 beta (CCL4)

Interleukin-12 Subunit p40 (IL-12p40)

Eotaxin-1 (CCL11)

Interleukin-23 (IL-23)

Matrix Metalloproteinase-3 (MMP-3)

Macrophage Inflammatory Protein-1 alpha (CCL-3)

Matrix Metalloproteinase-9 (MMP-9)

Matrix Metalloproteinase-2 (MMP-2)

Tissue Inhibitor of Metalloproteinase 1 (TIMP-1)

Stem Cell Factor (SCF)

Tumor Necrosis Factor alpha (TNF-alpha)

T-Cell-Specific Protein (CCL-5)

Tumor Necrosis Factor Receptor 2 (TNFR2)

Tumor Necrosis Factor β (TNF-β)

Vascular Cell Adhesion Molecule-1 (VCAM-1)

von Willebrand Factor (vWF)

Vascular Endothelial Growth Factor (VEGF)

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