Inflammatory and antiviral proteins at 24 hours after RV-1B infection in IFN-β/λ1-pre-treated healthy (n=6) and COPD (n=6) pBECs. IFN-β/λ1-pre-treatment before RV-1B infection led to a reduction of (A) IL-6 in healthy pBECs, but had no effect in COPD pBECs. (B) Similarly TNF-α protein was not affected by IFNs pre-treatment. (C) IFN-λ1, (D) CCL-5, and (E) CXCL-10 was significantly induced in pre-treated healthy and COPD pBECs. Results were presented as standard error of the mean (SEM). * p<0.05 versus the corresponding RV-1B. ^p<0.05 versus healthy RV-1B infected pBECs.