Skip to main content

Table 3 Relationships between the relative test values and hippocampal volumes in the groups with COPD of different severity

From: The unique alterations of hippocampus and cognitive impairment in chronic obstructive pulmonary disease

Test parameter

Mild-to-moderate COPD group hippocampal volume (n = 37)

Severe COPD group hippocampal volume (n = 48)

Total COPD group hippocampal volume (n = 85)

 

r

P

r

P

r

P

PaO2

0.55

<0.01

0.40

<0.01

0.51a

<0.01

PaCO2

0.15

NS

−0.14

NS

−0.15a

NS

SaO2

0.35

<0.05

0.19a

NS

0.29a

<0.01

FVC

0.13

NS

0.01

NS

0.21

<0.05

FEV1

0.14

NS

−0.12

NS

0.22a

<0.05

FEV1/FVC

−0.05

NS

−0.09

NS

0.10a

NS

MMSE

0.47

<0.01

0.19

NS

0.36

<0.01

S100B

−0.24

NS

−0.15

NS

−0.33

<0.01

  1. FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; PaO2 = arterial oxygen tension; PaCO2 = arterial carbon dioxide tension; SaO2 = blood oxygen saturation; MMSE = mini mental state exam; NS = no significant correlations. r = Pearson Correlation coefficient (except where indicated otherwise); a: Spearman rank correlation coefficient.