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Table 1 Characteristics of the study population of 257 asthmatic children residing in Mexico City 1998-2004

From: Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study

Characteristic

% or median(IQR)*

Gender (%male)

63.4

Age (years)

9.0 (7.2-11.0)

Height (cm)

134 (123–145)

BMI

18.5(16.1-21.6)

Antioxidant Study participants (%)

56.0

Vitamin C intake

Supplementation group (%)

30.4

Vitamin C intake in supplementation group (mg/d)

346 (329–375)

Vitamin C intake out of supplementation group (mg/d)

105 (84–131)

Asthma severity

Moderate- and severe-persistent asthma (%)

39.3

Mild-persistent asthma (%)

24.5

Mild-intermittent asthma (%)

36.2

Atopy (%)Ϫ

83.7

Genotype and allele frequency

n(%)

GSTM1 (Number of copies) †

0

93 (36.2)

1

129 (50.2)

2

35 (13.6)

GSTP1 rs1695

Val/Val

85 (33.1)

Ile/Val

113 (44.0)

Ile/Ile

59 (22.9)

Ile/Ile + Ile/Val

172 (66.9)

NQO1 rs1800566 ‡

 

Pro/Pro

67 (33.7)

Pro/Ser

88 (44.2)

Ser/Ser

44 (22.1)

Pro/Ser + Ser/Ser

132 (66.3)

Ethnicity (%) §

Mean (SD)

Native-American

70.9 (13.3)

European

26.2 (12.4)

African

2.9 (2.1)

  1. †n = 257; ‡n = 199; § n = 160.
  2. *Median(Q25-Q75); Ϫ Defined by skin test.