| Patients | Response | Overall survival | |||||
---|---|---|---|---|---|---|---|---|
Lines of systemic therapy | n | % | PR* | SD* | NE* | PD* | Median OS | 95% CI |
1 | 352 | 100 | 30.7 | 29.0 | 20.7 | 19.6 | 7.6 | 6.8-8.5 |
2 | 183 | 52.0 | 14.8 | 31.7 | 19.7 | 33.8 | 6.2 | 5.0-7.4 |
3 | 97 | 27.6 | 12.4 | 23.7 | 22.7 | 41.2 | 5.2 | 3.5-7.0 |
4 | 48 | 13.6 | 14.6 | 20.8 | 31.3 | 33.4 | 5.1 | 3.7-6.5 |
5 | 20 | 5.7 | 5.0 | 30.0 | 10 | 55.0 | 4.5 | 1.9-7.1 |
6 | 8 | 2.3 | 37.5 | 12.5 | 12.5 | 37.5 | 11.1 | 3.1-19.1 |
7 | 2 | 0.6 | 0 | 0 | 50 | 50 | Â | Â |