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Table 2 Cell count numbers in sputum after LPS challenge in each treatment group

From: Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist

Cell type (x106/g)

N

Geometric mean

P

P#

AZD8309

CV (%)

Placebo

CV (%)

Total cells

16

5.5

804

24

252

<0.001

0.003

Neutrophils

15

3.7

1595

17

252

0.027

0.028

Macrophages

15

1.9

354

3.6

523

0.15

0.11

  1. P = value by ANOVA; P# = value by Wilcoxon test.
  2. There is only n = 15 for the neutrophil and macrophage numbers because it was not possible to get a cell differential count from one of the sputum cytopsin preparations.
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Respiratory Research

ISSN: 1465-993X

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