Skip to main content

Table 3 Change in SGRQ and SF-36 scores after 12 weeks adjusted for baseline values

From: Azithromycin and cough-specific health status in patients with chronic obstructive pulmonary disease and chronic cough: a randomised controlled trial

 

Azithromycin

Placebo

Difference

95% CI

p Value

SGRQ

(n = 37)

(n = 37)

   

Total score

−6.6 ± 1.8

0.9 ±1.8

−7.5 ± 2.5

−12.5;-2.5

0.004

Symptoms

−9.2 ± 3.0

0.1 ± 3.0

−9.1 ± 4.2

−17.6;-.07

0.034

Activity

−4.1 ± 2.3

0.2 ± 2.3

−4.3 ± 3.2

−10.7;2.1

0.18

Impact

−7.3 ± 2.0

1.6 ± 2.0

−8.9 ± 2.8

−14.5;-3.3

0.002

SF-36

(n = 37)

(n = 37)

   

General health*

4.5 ± 2.4

−3.8 ± 2.4

8.3 ± 3.4

1.6;15

0.016

Physical functioning

5.5 ± 2.2

0.7 ± 2.3*

4.8 ± 3.2

−1.5;11.1

0.13

Bodily pain

5.6 ± 3.3

−0.9 ± 3.3

6.5 ± 4.7

−2.9;15.9

0.17

Vitality*

4.0 ± 2.4

−2.0 ± 2.4

6.0 ± 3.4

−0.8;12.9

0.08

Role physical

16.2 ± 5.4

−1.1 ± 5.4

17.3 ± 7.6

2.2;32.5

0.025

Role emotional

−0.4 ± 5.6

−6.3 ± 5.6

5.9 ± 7.9

−9.8;21.7

0.46

Social functioning

4.4 ± 3.1

−8.5 ± 3.1

12.9 ± 4.4

4.0;21.7

0.005

Mental health*

2.2 ± 1.9

−3.5 ± 1.9

5.7 ± 2.7

0.4;11.0

0.037

  1. All scores are presented as mean with standard error.
  2. SGRQ, St. George’s respiratory questionnaire. Scores range from 0-100. A low score indicates a good health status, the minimal important difference is 4; SF-36, Short-form 36. Scores range from 0-100, higher scores represent better health status. The minimal important difference is 4.
  3. *n = 36.