Table 1 Subject characteristics for bronchial biopsies primary bronchial epithelial cells
Healthy controls | Mild asthmatics | Severe asthmatics | |
|---|---|---|---|
Biopsies for immunohistochemical staining | |||
Age (years) | 30.3 ± 15.2 | 34.2 ± 13.1 | 50.2 ± 15.0 |
Sex | 1 M/4 F | 3 M/2 F | 4 M/1 F |
FEV1 (%) | 105.8 ± 6.42 | 95.6 ± 13.4 | 56.8 ± 23.2 |
Atopy | 2 | 5 | 5 |
Medication (μg/day) | 890 ± 690/200 | ||
(inhaled corticosteroid/ long-acting β2 agonist) | |||
Primary bronchial epithelial cells | |||
Age (years) | 28.8 ± 11.0 | 21.8 ± 1.5 | 49.8 ± 16.0 |
Sex | 4 M/1 F | 2 M/3 F | 2 M/3 F |
PC20 (mg/ml) | 135.0 ± 68.8 | 4.2 ± 3.9 | ND |
FEV1 (%) | 96.0 ± 13.7 | 95.0 ± 5.1 | 54.0 ± 17.0 |
Atopy | 0 | 5 | 4 yes/1 no |
Medication (μg/day) | 1050 ± 255/100 | ||
(inhaled corticosteroid/ long-acting β2 agonist) |