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Table 2 BAL fluid analysis

From: Fluticasone impact on airway dendritic cells in smokers: a randomized controlled trial

 

Placebo

Fluticasone

Fluticasone/Salmeterol

Time point

A

B

A

B

A

B

n

14

14

14

14

14

14

Recovery (ml BAL fluid)

62 (45 - 67)

64 (48 - 71)

63 (56–70)

65 (37–72)

62 (55–65)

62 (54–70)

Total cells (10 3 /ml BAL fluid)

121 (17–487)

190 (35–469)

81 (38–284)

93 (6–217)

125 (36–409)

97* (25–339)

Macrophages (10 3 /ml BAL fluid)

114 (15–447)

181 (34–459)

75 (32–263)

86 (5–205)

119 (32–397)

88* (22–315)

Lymphocytes (10 3 /ml BAL fluid)

7.2 (0.5 - 34.1)

5.6 (0.7 - 28.2)

2.7 (0.6 - 13.1)

4.1 (0.6 - 7.8)

3.0 (1.0 - 39.1)

3.2 (0.7 - 14.2)

Neutrophils (10 3 /ml BAL fluid)

2.1 (0.3 - 12.0)

1.4 (0.0 - 5.0)

1.6 (0.6 - 5.1)

1.2 (0.2 - 6.1)

2.9 (0.1 - 5.4)

0.7* (0.0 - 6.1)

Eosinophils (10 3 /ml BAL fluid)

0.4 (0.0 - 5.1)

0.3 (0.0 - 4.2)

0.5 (0.0 - 2.8)

0.2 (0.0 - 1.2)

0.1 (0.0 - 3.0)

0.2 (0.0 - 3.4)

  1. Shown are median values (minimum – maximum) of the recovery of BAL fluid, the total concentration of BAL fluid cells and the concentrations of macrophages, lymphocytes, neutrophils and eosinophils in BAL fluid of the participants (median values, minimum – maximum) in the 3 study arms (Placebo, Fluticasone, Fluticasone/Salmeterol), at the time points A (prior to treatment) and B (directly after treatment). Significant differences between the time points (p < 0.05) are marked with an asterisk (*).